General Information of the Compound
| Compound ID |
CP0271912
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| Compound Name |
7-[1-(2,6-dichloro-3-fluorophenyl)propoxy]-3-(1-piperidin-4-ylpyrazol-4-yl)furo[3,2-c]pyridin-6-amine
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| Structure |
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| Formula |
C24H24Cl2FN5O2
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| Molecular Weight |
504.393
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| Canonical SMILES |
CCC(Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
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| InChI |
InChI=1S/C24H24Cl2FN5O2/c1-2-19(20-17(25)3-4-18(27)21(20)26)34-23-22-15(10-30-24(23)28)16(12-33-22)13-9-31-32(11-13)14-5-7-29-8-6-14/h3-4,9-12,14,19,29H,2,5-8H2,1H3,(H2,28,30)
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| InChIKey |
RSBGPRGRBPDFBV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01201, Hepatocyte growth factor receptor
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000413 | MKN45 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 3600 nM
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