General Information of the Compound
| Compound ID |
CP0258338
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| Compound Name |
7-[3,5-dimethoxy-N-[2-(propan-2-ylamino)ethyl]anilino]-3-(1-methylpyrazol-4-yl)pyrido[1,2-a]pyrimidin-4-one
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| Formula |
C25H30N6O3
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| Molecular Weight |
462.554
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| Canonical SMILES |
COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(-c3cnn(C)c3)c(=O)n2c1
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| InChI |
InChI=1S/C25H30N6O3/c1-17(2)26-8-9-30(20-10-21(33-4)12-22(11-20)34-5)19-6-7-24-27-14-23(25(32)31(24)16-19)18-13-28-29(3)15-18/h6-7,10-17,26H,8-9H2,1-5H3
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| InChIKey |
HRSOTZFHFDXFAE-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01115, Fibroblast growth factor receptor 2
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2