General Information of the Compound
Compound ID
CP0256962
Compound Name
2-[(1S)-5-[3-(4-{4H,5H,6H-cyclopenta[d][1,3]thiazol-2-yl}phenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
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Structure
Formula
C26H27NO4S
Molecular Weight
449.572
Canonical SMILES
OC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(cc3)-c3nc4CCCc4s3)ccc12
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InChI
InChI=1S/C26H27NO4S/c28-25(29)16-19-6-5-18-15-21(11-12-22(18)19)31-14-2-13-30-20-9-7-17(8-10-20)26-27-23-3-1-4-24(23)32-26/h7-12,15,19H,1-6,13-14,16H2,(H,28,29)/t19-/m0/s1
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InChIKey
ZPYXSSUHSIOZJR-IBGZPJMESA-N
Physicochemical Property
logP
5.6512
Rotatable Bonds
9
Heavy Atom Count
32
Polar Areas
68.65
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16110488
SID: 24757320
ChEMBL ID
CHEMBL221101
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02973, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
EC50 = 1200 nM
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