General Information of the Compound
Compound ID
CP0254955
Compound Name
1-(6-{13-[4-(trifluoromethyl)phenyl]tridecanamido}quinolin-2-yl)-1-azabicyclo[2.2.2]octan-1-ylium
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Structure
Formula
C36H47F3N3O+
Molecular Weight
594.786
Canonical SMILES
FC(F)(F)c1ccc(CCCCCCCCCCCCC(=O)Nc2ccc3nc(ccc3c2)[N+]23CCC(CC2)CC3)cc1
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InChI
InChI=1S/C36H46F3N3O/c37-36(38,39)31-16-13-28(14-17-31)11-9-7-5-3-1-2-4-6-8-10-12-35(43)40-32-18-19-33-30(27-32)15-20-34(41-33)42-24-21-29(22-25-42)23-26-42/h13-20,27,29H,1-12,21-26H2/p+1
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InChIKey
DHGGHSPKBKPGOG-UHFFFAOYSA-O
Physicochemical Property
logP
9.8469
Rotatable Bonds
15
Heavy Atom Count
43
Polar Areas
41.99
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
43

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44417956
ChEMBL ID
CHEMBL263686
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01388, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM