General Information of the Compound
Compound ID
CP0201349
Compound Name
9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-naphthalen-2-ylmethyl-5,8,11,14,17-pentaoxo-1,4,7,10,13pentaaza-cycloheptadecane-3-carboxylic acid
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Structure
Formula
C37H44N10O6
Molecular Weight
724.823
Canonical SMILES
NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)CCC(=O)NCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O
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InChI
InChI=1S/C37H44N10O6/c38-33(50)30-20-43-31(48)13-14-32(49)44-28(17-21-11-12-22-6-1-2-7-23(22)16-21)35(52)45-27(10-5-15-41-37(39)40)34(51)46-29(36(53)47-30)18-24-19-42-26-9-4-3-8-25(24)26/h1-4,6-9,11-12,16,19,27-30,42H,5,10,13-15,17-18,20H2,(H2,38,50)(H,43,48)(H,44,49)(H,45,52)(H,46,51)(H,47,53)(H4,39,40,41)/t27-,28-,29+,30?/m0/s1
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InChIKey
OXIJPFTXSOSKGQ-BLFWRVEASA-N
Physicochemical Property
logP
-0.29593
Rotatable Bonds
9
Heavy Atom Count
53
Polar Areas
266.28
Hydrogen Bond Donor Count
10
Hydrogen Bond Acceptor Count
7
Complexity
53

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44347105
ChEMBL ID
CHEMBL331728
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01804, Melanocortin receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4800 nM