General Information of the Compound
| Compound ID |
CP0181125
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| Compound Name |
Demethyl-AMPA
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| Synonyms |
nociceptin(1-13)NH2
178064-02-3
AC1O44IO
AKOS024456547
BDBM50106479
BDBM85822
CHEMBL384755
Demethyl-AMPA
FGGFTGARKSARK
GTPL1682
H-FGGFTGARKSARK-NH2
N/OFQ(1-13)NH2
N/OFQ-(1-13)-NH2
NC(1-13)NH2
NCGC00167157-01
Nociceptin (1-13)NH2
Nociceptin Orphanin FQ1-13-NH2
Nociceptin analogueNC(1-13)-NH2
OFQ/N
OFQ/N (1-11)
RHMALYOXPBRJBG-CGUXNFSNSA-N
nociceptin(1-13)-NH2
nociceptin(1-13)NH2
nociceptin/orphanin FQ(1-13)NH2
orphanin FQ(1-13)NH2
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| Structure |
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| Formula |
C61H100N22O15
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| Molecular Weight |
1381.61
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| Canonical SMILES |
C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(N)=O
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| InChI |
InChI=1S/C61H100N22O15/c1-34(75-47(87)32-74-59(98)49(36(3)85)83-57(96)44(29-38-18-8-5-9-19-38)77-48(88)31-72-46(86)30-73-53(92)39(64)28-37-16-6-4-7-17-37)51(90)79-43(23-15-27-71-61(68)69)55(94)81-41(21-11-13-25-63)56(95)82-45(33-84)58(97)76-35(2)52(91)80-42(22-14-26-70-60(66)67)54(93)78-40(50(65)89)20-10-12-24-62/h4-9,16-19,34-36,39-45,49,84-85H,10-15,20-33,62-64H2,1-3H3,(H2,65,89)(H,72,86)(H,73,92)(H,74,98)(H,75,87)(H,76,97)(H,77,88)(H,78,93)(H,79,90)(H,80,91)(H,81,94)(H,82,95)(H,83,96)(H4,66,67,70)(H4,68,69,71)/t34-,35-,36+,39-,40-,41-,42-,43-,44-,45-,49-/m0/s1
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| InChIKey |
RHMALYOXPBRJBG-CGUXNFSNSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Clinical Information about the Compound
Drug 1 ( N/OFQ-(1-13)-NH2 )
| Drug Name | N/OFQ-(1-13)-NH2 | ||
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| Target(s) |
Nociceptin receptor (OPRL1)
Agonist
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