General Information of the Compound
| Compound ID |
CP0158674
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
US9238644, 56
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H28F3N7O
|
||||||||||||||||||
| Molecular Weight |
487.53
|
||||||||||||||||||
| Canonical SMILES |
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(c2)C2CCNCC2)ncc1C(F)(F)F
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H28F3N7O/c1-15(22(28)35)19-5-3-2-4-16(19)6-7-21-20(24(25,26)27)13-30-23(33-21)32-17-12-31-34(14-17)18-8-10-29-11-9-18/h2-5,12-15,18,29H,6-11H2,1H3,(H2,28,35)(H,30,32,33)
Show/Hide
|
||||||||||||||||||
| InChIKey |
ZYAMSUYXTXWKGM-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3