General Information of the Compound
Compound ID
CP0154491
Compound Name
9-[[3,5-diethoxy-4-(4-fluorophenyl)phenyl]methyl]-3-pyridin-3-ylsulfonyl-3,9-diazaspiro[5.5]undecane
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Structure
Formula
C31H38FN3O4S
Molecular Weight
567.727
Canonical SMILES
CCOc1cc(CN2CCC3(CC2)CCN(CC3)S(=O)(=O)c2cccnc2)cc(OCC)c1-c1ccc(F)cc1
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InChI
InChI=1S/C31H38FN3O4S/c1-3-38-28-20-24(21-29(39-4-2)30(28)25-7-9-26(32)10-8-25)23-34-16-11-31(12-17-34)13-18-35(19-14-31)40(36,37)27-6-5-15-33-22-27/h5-10,15,20-22H,3-4,11-14,16-19,23H2,1-2H3
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InChIKey
CDOLWFQFQZOXNZ-UHFFFAOYSA-N
Physicochemical Property
logP
5.752
Rotatable Bonds
9
Heavy Atom Count
40
Polar Areas
71.97
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145979224
ChEMBL ID
CHEMBL4280531
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01196, Somatostatin receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
   TI
   LI
   LO
   TS