General Information of the Compound
Compound ID
CP0154074
Compound Name
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3,5-dimethylbenzoate
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Structure
Formula
C17H23NO2
Molecular Weight
273.376
Canonical SMILES
CN1C2CCC1CC(C2)OC(=O)c1cc(C)cc(C)c1
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InChI
InChI=1S/C17H23NO2/c1-11-6-12(2)8-13(7-11)17(19)20-16-9-14-4-5-15(10-16)18(14)3/h6-8,14-16H,4-5,9-10H2,1-3H3
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InChIKey
HDDNYFLPWFSBLN-UHFFFAOYSA-N
Physicochemical Property
logP
3.08544
Rotatable Bonds
2
Heavy Atom Count
20
Polar Areas
29.54
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2837530
SID: 14824210
ChEMBL ID
CHEMBL40883
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01552, Nuclear receptor subfamily 1 group I member 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000514 DPX2 Homo sapiens (Human)  2
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
2
EC50 = 15800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 14100 nM