General Information of the Compound
| Compound ID |
CP0135449
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| Compound Name |
(E)-N-Hydroxy-3-[4-(4-sulfamoyl-benzenesulfonylamino)-phenyl]-acrylamide
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| Structure |
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| Formula |
C15H15N3O6S2
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| Molecular Weight |
397.434
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| Canonical SMILES |
NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1
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| InChI |
InChI=1S/C15H15N3O6S2/c16-25(21,22)13-6-8-14(9-7-13)26(23,24)18-12-4-1-11(2-5-12)3-10-15(19)17-20/h1-10,18,20H,(H,17,19)(H2,16,21,22)/b10-3+
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| InChIKey |
JLTDXXRPDVFXJE-XCVCLJGOSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000067 | HCT 116 | Homo sapiens (Human) | 1 |
| 1 |
EC50 > 42000 nM
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TI
LI
LO
TS
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