General Information of the Compound
Compound ID
CP0128439
Compound Name
2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)nicotinamide
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Structure
Formula
C14H16N4O3S
Molecular Weight
320.374
Canonical SMILES
NCCNC(=O)c1cc(cnc1N)-c1scc2OCCOc12
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InChI
InChI=1S/C14H16N4O3S/c15-1-2-17-14(19)9-5-8(6-18-13(9)16)12-11-10(7-22-12)20-3-4-21-11/h5-7H,1-4,15H2,(H2,16,18)(H,17,19)
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InChIKey
RSXFSSZTSZFLPI-UHFFFAOYSA-N
Physicochemical Property
logP
0.852
Rotatable Bonds
4
Heavy Atom Count
22
Polar Areas
112.49
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46230185
SID: 99207864
ChEMBL ID
CHEMBL599171
Table of Molecular Bioactivities Related to the Compound
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
GI50 = 28000 nM
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