General Information of the Compound
| Compound ID |
CP0121178
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| Compound Name |
US9340555, 85
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| Structure |
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| Formula |
C24H20FN3O3S
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| Molecular Weight |
449.507
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| Canonical SMILES |
CCNC(=O)c1cc2nccc(Oc3cccc(c3)C(=O)Nc3cc(C)ccc3F)c2s1
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| InChI |
InChI=1S/C24H20FN3O3S/c1-3-26-24(30)21-13-19-22(32-21)20(9-10-27-19)31-16-6-4-5-15(12-16)23(29)28-18-11-14(2)7-8-17(18)25/h4-13H,3H2,1-2H3,(H,26,30)(H,28,29)
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| InChIKey |
GSSGNGAODUGVCN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01142, Vascular endothelial growth factor receptor 1
Protein ID: PT00864, Vascular endothelial growth factor receptor 2