General Information of the Compound
Compound ID
CP0114213
Compound Name
7-(2-fluoro-6-methoxyphenyl)-N-(oxan-4-yl)-1,3-benzoxazol-2-amine
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Structure
Formula
C19H19FN2O3
Molecular Weight
342.37
Canonical SMILES
COc1cccc(F)c1-c1cccc2nc(NC3CCOCC3)oc12
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InChI
InChI=1S/C19H19FN2O3/c1-23-16-7-3-5-14(20)17(16)13-4-2-6-15-18(13)25-19(22-15)21-12-8-10-24-11-9-12/h2-7,12H,8-11H2,1H3,(H,21,22)
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InChIKey
KVPIMMONOVKADW-UHFFFAOYSA-N
Physicochemical Property
logP
4.2334
Rotatable Bonds
4
Heavy Atom Count
25
Polar Areas
56.52
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90645218
ChEMBL ID
CHEMBL3297844
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06683, Ribosomal protein S6 kinase alpha-2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 > 20000 nM
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