General Information of the Compound
Compound ID
CP0095792
Compound Name
[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[3-[4-(1,4-oxazepan-4-ylmethyl)phenoxy]azetidin-1-yl]methanone
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Structure
Formula
C25H28N4O5
Molecular Weight
464.522
Canonical SMILES
COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CCCOCC2)cc1
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InChI
InChI=1S/C25H28N4O5/c1-31-20-9-5-19(6-10-20)23-26-27-24(34-23)25(30)29-16-22(17-29)33-21-7-3-18(4-8-21)15-28-11-2-13-32-14-12-28/h3-10,22H,2,11-17H2,1H3
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InChIKey
YJQKVKQPRXATHT-UHFFFAOYSA-N
Physicochemical Property
logP
2.8709
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
90.16
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 123471111
ChEMBL ID
CHEMBL3787028
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 34 nM
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