General Information of the Compound
Compound ID
CP0094196
Compound Name
2-(pyridin-2-yl)-1H-benzo[d]imidazole
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Synonyms
1137-68-4
1H-Benzimidazole, 2-(2-pyridinyl)-
1H-Benzimidazole, 2-(pyridinyl)-
2(2-Pyridyl)benzimidazole
2-(2'-Pyrido)benzimidazole
2-(2-Pyridyl)benzimidazole
2-(2-Pyridyl)benzimidazole, 99%
2-(2-pyridyl) benzimidazole
2-(pyridin-2-yl)-1H-1,3-benzodiazole
2-(pyridin-2-yl)-1H-benzimidazole
2-(pyridin-2-yl)-1H-benzo[d]imidazole
2-Pyridin-2-yl-1H-benzoimidazole
2-pyridin-2-yl-1H-benzimidazole
AC1L2EXP
ACMC-20aime
CHEMBL72683
EINECS 214-508-7
MLS000554415
NSC 110942
NSC 32814
YNFBMDWHEHETJW-UHFFFAOYSA-N
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Structure
Formula
C12H9N3
Molecular Weight
195.225
Canonical SMILES
c1ccc(nc1)-c1nc2ccccc2[nH]1
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InChI
InChI=1S/C12H9N3/c1-2-6-10-9(5-1)14-12(15-10)11-7-3-4-8-13-11/h1-8H,(H,14,15)
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InChIKey
YNFBMDWHEHETJW-UHFFFAOYSA-N
CAS
1137-68-4
Physicochemical Property
logP
2.6249
Rotatable Bonds
1
Heavy Atom Count
15
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
15

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70821
SID: 14797397
ChEMBL ID
CHEMBL72683
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480
 Cell Line Info 
Homo sapiens (Human)  1
1
Potency ~ 4109.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00973, Methionine aminopeptidase 2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 13300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( 2-(pyridin-2-yl)-1H-benzo[d]imidazole )
Drug Name 2-(pyridin-2-yl)-1H-benzo[d]imidazole
Target(s)
Methionine aminopeptidase 2 (METAP2)
 Target Info 
Inhibitor