General Information of the Compound
| Compound ID |
CP0088790
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| Compound Name |
5-(1-methylpyrazol-4-yl)-3-(2H-pyrazolo[3,4-b]pyridin-3-ylmethyl)triazolo[4,5-b]pyrazine
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| Structure |
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| Formula |
C15H12N10
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| Molecular Weight |
332.331
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| Canonical SMILES |
Cn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1
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| InChI |
InChI=1S/C15H12N10/c1-24-7-9(5-18-24)11-6-17-14-15(19-11)25(23-22-14)8-12-10-3-2-4-16-13(10)21-20-12/h2-7H,8H2,1H3,(H,16,20,21)
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| InChIKey |
LLJLMQVEVSKRLS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01201, Hepatocyte growth factor receptor
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000450 | NCI-H441 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 66 nM
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