General Information of the Compound
Compound ID
CP0083519
Compound Name
2-(5-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyloxy)-1H-indol-1-yl)acetic acid
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Structure
Formula
C25H20F3NO4
Molecular Weight
455.432
Canonical SMILES
OC(=O)Cn1ccc2cc(OCc3cccc(COc4ccc(cc4)C(F)(F)F)c3)ccc12
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InChI
InChI=1S/C25H20F3NO4/c26-25(27,28)20-4-6-21(7-5-20)32-15-17-2-1-3-18(12-17)16-33-22-8-9-23-19(13-22)10-11-29(23)14-24(30)31/h1-13H,14-16H2,(H,30,31)
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InChIKey
HPRZJTYQTBHRKL-UHFFFAOYSA-N
Physicochemical Property
logP
5.9027
Rotatable Bonds
8
Heavy Atom Count
33
Polar Areas
60.69
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44432409
ChEMBL ID
CHEMBL231689
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00909, Peroxisome proliferator-activated receptor delta
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 254 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM