General Information of the Compound
| Compound ID |
CP0060921
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| Compound Name |
US10065963, 32c
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| Synonyms |
(4R)-4-(3-((1S)-1-(4-Amino-3-methyl-1H-pyrazolo(3,4-d)pyrimidin-1-yl)ethyl)-5-chloro-2-ethoxy-6-fluorophenyl)pyrrolidin-2-one
(4R)-4-{3-[(1S)-1-(4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-ethoxy-6-fluorophenyl}pyrrolidin-2-one
(R)-4-(3-((S)-1-(4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-chloro-2-ethoxy-6-fluorophenyl)pyrrolidin-2-one
1426698-88-5
1426698-88-5 (free base)
2-Pyrrolidinone, 4-(3-((1S)-1-(4-amino-3-methyl-1H-pyrazolo(3,4-d)pyrimidin-1-yl)ethyl)-5-chloro-2-ethoxy-6-fluorophenyl)-, (4R)-
BDBM272573
CHEMBL4297615
CS-0033435
D11437
DB14867
EX-A2638
HY-109068
INCB-050465
INCB-050465 free base
INCB050465
INCB050465 free base
OS7097575K
Parsaclisib
Parsaclisib (USAN/INN)
Parsaclisib [INN]
Parsaclisib [USAN:INN]
Parsaclisib [USAN]
Parsaclisib free base
SCHEMBL14736228
UNII-OS7097575K
US10065963, 32c
WHO 10589
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| Structure |
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| Formula |
C20H22ClFN6O2
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| Molecular Weight |
432.887
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| Canonical SMILES |
CCOc1c(cc(Cl)c(F)c1[C@@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12
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| InChI |
InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11-/m0/s1
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| InChIKey |
ZQPDJCIXJHUERQ-QWRGUYRKSA-N
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| CAS |
1426698-88-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound