General Information of the Compound
| Compound ID |
CP0052205
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| Compound Name |
5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue
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| Synonyms |
Antrypol
Belganyl
Farma
Farma 939
Fourneau
Germanin
Germanin (TN)
Moranyl
Naganil
Naganin
Naganine
Naganol
Naganol 6 Na
Naphuride
SGCTO-001
SURAMIN SODIUM
SVR
Sodium suramin
Suramin
Suramine
Suramine sodium
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| Structure |
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| Formula |
C51H40N6O23S6
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| Molecular Weight |
1297.302
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| Canonical SMILES |
Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O
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| InChI |
InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)
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| InChIKey |
FIAFUQMPZJWCLV-UHFFFAOYSA-N
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| CAS |
145-63-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound
Drug 1 ( Suramin )
| Drug Name | Suramin | ||
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| Company | Bayer Pharmaceuticals Corporation | ||
| Indication | |||
| Target(s) |
Follicle-stimulating hormone receptor (FSHR)
Antagonist
Heparanase (HPSE)
Inhibitor
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