General Information of the Compound
| Compound ID |
CP0052064
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| Compound Name |
2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole
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| Synonyms |
2-[4-(3,4-dimethylphenyl)piperazin-1-ylmethyl]-1h-benzimidazole
2-[[4-(3,4-dimethylphenyl)piperazin-1-yl]methyl]-1H-benzimidazole
A 381393
A-381,393
A-381393
BDBM50150141
CHEMBL127257
GTPL8441
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| Structure |
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| Formula |
C20H24N4
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| Molecular Weight |
320.44
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| Canonical SMILES |
Cc1ccc(cc1C)N1CCN(Cc2nc3ccccc3[nH]2)CC1
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| InChI |
InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22)
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| InChIKey |
SAQMCVDGOIRQTC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound
Drug 1 ( A-381393 )
| Drug Name | A-381393 | ||
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| Target(s) |
Dopamine D4 receptor (D4R)
Antagonist
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