General Information of the Compound
Compound ID
CP0046924
Compound Name
(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
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Synonyms
(5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
(5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester
(5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester
2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester
2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI)
5-Benzoyl-2-benzimidazolecarbamic acid methyl ester
5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester
Abello Farmacia Brand of Mebendazole
Anti Worm
Anti-Worm
Antiox (TN)
Ardeypharm Brand of Mebendazole
Bantenol
Banworm
Besantin
Boots Brand of Mebendazole
Boots Threadworm Treatment
Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester
Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI)
Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester
Degort's Brand of Mebendazole
Diba Brand of Mebendazole
Elfar Brand of Mebendazole
Equivurm Plus
Esteve Brand of Mebendazole
Healthypharm Brand of Mebendazole
Janssen Brand of Mebendazole
Leidapharm Brand of Mebendazole
Lomper
MBDZ
MEBENDAZOLE, 99%
Madicure
Mebendan
Mebendazol
Mebendazol [INN-Spanish]
Mebendazole
Mebendazole (JAN/USP)
Mebendazole (JAN/USP/INN)
Mebendazole [USAN:INN:BAN:JAN]
Mebendazole(USAN)
Mebendazolum
Mebendazolum [INN-Latin]
Mebenoazole
Mebenvet
Mebex
Mebutar
Methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
Methyl 5-benzoyl-2-benzimidazolecarbamate
Methyl 5-benzoyl-2-benzimidazolylcarbamate
Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate
Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate
Methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate
Methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate
Methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate
Methyl5-benzoyl benzimidazole-2-carbamate
N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle
N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French]
N-2 (5-Benzoyl-benzimidazole) carbamate de methyle
N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French]
Norgine Brand of Mebendazole
Noverme
Ovex (TN)
Ovitelmin
Pantelmin
Pfizer Brand of Mebendazole
Pripsen (TN)
Pripsen Mebendazole
R 17,635
R 17635
R-17635
R17635
SSL Brand of Mebendazole
Sqworm
Streger Brand of Mebendazole
Sufil
Surfont
Taxandria Brand of Mebendazole
Tedec Meiji Brand of Mebendazole
Telmin
Vermicidin
Vermicol
Vermidil
Vermin
Vermirax
Vermox
Vermox (TN)
Verpanyl
Versid
Wormkuur
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Structure
Formula
C16H13N3O3
Molecular Weight
295.298
Canonical SMILES
COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1ccccc1
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InChI
InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
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InChIKey
OPXLLQIJSORQAM-UHFFFAOYSA-N
CAS
31431-39-7
Physicochemical Property
logP
2.9722
Rotatable Bonds
3
Heavy Atom Count
22
Polar Areas
84.08
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 4030
SID: 144214057
ChEMBL ID
CHEMBL685
DrugBank ID
DB00643
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05334, ATP-binding cassette sub-family C member 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 15500 nM
   TI
   LI
   LO
   TS
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 285.7 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Mebendazole )
Drug Name Mebendazole
Company Janssen Pharmaceutica
Indication
Worm infection
Approved