General Information of the Compound
Compound ID
CP0041831
Compound Name
2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester
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Synonyms
ATROMID-S (TN)
AY 61123
AY-61123
Amotril
Amotril S
Angiokapsul
Anparton
Antilipid
Antilipide
Apolan
Arterioflexin
Arterosol
Artevil
Ateculon
Ateriosan
Athebrate
Atheromide
Atheropront
Athranid-wirkstoff
Athromidin
Atrolen
Atromid
Atromid S
Atromid-S
Atromid-S (TN)
Atromid-S, Clofibrate
Atromida
Atromidin
Atrovis
Azionyl
BML2-F02
Bioscleran
Bresit
C 6643
CPIB
Cartagyl
Chlorfenisate
Chlorophenoxyisobutyrate, Ethyl
Chlorphenisate
Cinnarizin
Citiflus
Claripex
Claripex CPIB
Cloberat
Clobrat
Clobren-5F
Clobren-SF
Clofar
Clofibate
Clofibram
Clofibrat
Clofibrate
Clofibrate (CLOF)
Clofibrate (JP15/USP/INN)
Clofibrate [USAN:INN:BAN:JAN]
Clofibrato
Clofibrato [INN-Spanish]
Clofibrato [Spanish]
Clofibratum
Clofibratum [INN-Latin]
Clofibric Acid, Ethyl Ester
Clofinit
Clofipront
Delipid
Deliva
Dura clofibrat
ELPI
EPIB
Ethyl 2-(4-chlorophenoxy)isobutyrate
Ethyl 2-(p-chlorophenoxy)isobutyrate
Ethyl alpha-(4-chlorophenoxy)isobutyrate
Ethyl alpha-(p-chlorophenoxy)isobutyrate
Ethyl alpha-p-chlorophenoxyisobutyrate
Ethyl chlorophenoxyisobutyrate
Ethyl clofibrate
Ethyl p-chlorophenoxyisobutyrate
Ethyl para-chlorophenoxyisobutyrate
Ethyl-alpha-p-chlorophenoxy-isobutyrate
Fibralem
Gerastop
Hyclorate
Klofibrat
Klofiran
Levatrom
Lipamid
Lipavil
Lipavlon
Lipide 500
Lipidsenker
Lipofacton
Lipomid
Liponorm
Liporeduct
Liporil
Liposid
Liprin
Liprinal
Lobetrin
Miscleron
Misclerone
Miskleron
Negalip
Neo-Atomid
Neo-Atromid
Normalip
Normat
Normet
Normolipol
Novofibrate
Oxan 600
Persantinat
Recolip
Regardin
Regelan
Regelan N
Robigram
Scrobin
Serofinex
Serotinex
Skerolip
Sklerepmexe
Sklero
Sklero-Tablinen
Sklero-tablinene
Sklero-tabuls
Sklerolip
Skleromex
Skleromexe
Ticlobran
Vincamin compositum
Xyduril
Yoclo
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Structure
Formula
C12H15ClO3
Molecular Weight
242.702
Canonical SMILES
CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
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InChI
InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
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InChIKey
KNHUKKLJHYUCFP-UHFFFAOYSA-N
CAS
637-07-0
Physicochemical Property
logP
3.0605
Rotatable Bonds
4
Heavy Atom Count
16
Polar Areas
35.53
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
16

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2796
SID: 22395216
ChEMBL ID
CHEMBL565
DrugBank ID
DB00636
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04542, Bile salt export pump
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 71000 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Clofibrate )
Drug Name Clofibrate
Company Ayerst Laboratories Inc
Indication
Dysbetalipoproteinemia
Approved
Target(s)
Lipoprotein lipase (LPL)
Activator