General Information of the Compound
| Compound ID |
CP0036044
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
(+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Show/Hide
|
||||||||||||||||||
| Synonyms |
EX-527
SEN-0014196
SEN-196
SIRT1 inhibitors (Huntingtons disease), Elixir/Siena
Sirtuin-1 inhibitors (oral, Huntington's disease), Elixir/Siena
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C13H13ClN2O
|
||||||||||||||||||
| Molecular Weight |
248.713
|
||||||||||||||||||
| Canonical SMILES |
NC(=O)C1CCCc2c1[nH]c1ccc(Cl)cc21
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)
Show/Hide
|
||||||||||||||||||
| InChIKey |
FUZYTVDVLBBXDL-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
| DrugBank ID | |||||||||||||||||||
Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound