General Information of the Compound
| Compound ID |
CP0030986
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| Compound Name |
N-(4-(2-propylhydrazine-1- carbonyl)benzyl)cinnamamide
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| Structure |
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| Formula |
C20H23N3O2
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| Molecular Weight |
337.423
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| Canonical SMILES |
CCCNNC(=O)c1ccc(CNC(=O)\C=C\c2ccccc2)cc1
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| InChI |
InChI=1S/C20H23N3O2/c1-2-14-22-23-20(25)18-11-8-17(9-12-18)15-21-19(24)13-10-16-6-4-3-5-7-16/h3-13,22H,2,14-15H2,1H3,(H,21,24)(H,23,25)/b13-10+
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| InChIKey |
MHZUZIALEUTHIU-JLHYYAGUSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT00995, Histone deacetylase 3
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000091 | MV4-11 | Homo sapiens (Human) | 1 |
| 1 |
EC50 = 36.37 nM
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TI
LI
LO
TS
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| CL000186 | RPMI-8226 | Homo sapiens (Human) | 1 |
| 1 |
EC50 > 10000 nM
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TI
LI
LO
TS
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