General Information of the Compound
Compound ID
CP0030279
Compound Name
(5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-amide
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Synonyms
(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
183718-77-6
198022-70-7
5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-
AC1O7GXA
AM 404
AM-404
CHEMBL39878
CPD000449274
N-(4-Hydroxyphenyl)-arachidonylamide
N-(4-Hydroxyphenyl)arachidonoyl amide
N-(4-Hydroxyphenyl)arachidonylamide
N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide
N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
NCGC00025010-01
SMR000449274
SR-01000597390
Tocris-1116
UNII-XVJ94H0U21
XVJ94H0U21
am404
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Structure
Formula
C26H37NO2
Molecular Weight
395.587
Canonical SMILES
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc(O)cc1
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InChI
InChI=1S/C26H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26(29)27-24-20-22-25(28)23-21-24/h6-7,9-10,12-13,15-16,20-23,28H,2-5,8,11,14,17-19H2,1H3,(H,27,29)/b7-6-,10-9-,13-12-,16-15-
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InChIKey
IJBZOOZRAXHERC-DOFZRALJSA-N
Physicochemical Property
logP
7.4764
Rotatable Bonds
15
Heavy Atom Count
29
Polar Areas
49.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 6604822
SID: 26683768
ChEMBL ID
CHEMBL39878
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00834, Cannabinoid receptor 2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( AM-404 )
Drug Name AM-404
Target(s)
Cannabinoid receptor 2 (CB2)
 Target Info 
Inhibitor
Cannabinoid receptor 1 (CB1)
 Target Info 
Inhibitor