General Information of the Compound
| Compound ID |
CP0014147
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| Compound Name |
N-hydroxy-3-[1-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinolin-2-yl]propanamide
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| Structure |
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| Formula |
C19H19F3N2O2
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| Molecular Weight |
364.367
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| Canonical SMILES |
ONC(=O)CCN1CCc2ccccc2C1c1cccc(c1)C(F)(F)F
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| InChI |
InChI=1S/C19H19F3N2O2/c20-19(21,22)15-6-3-5-14(12-15)18-16-7-2-1-4-13(16)8-10-24(18)11-9-17(25)23-26/h1-7,12,18,26H,8-11H2,(H,23,25)
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| InChIKey |
VPNDNCYGWBYJFG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2