General Information of the Compound
| Compound ID |
CP0013015
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| Compound Name |
N-[4-(2-oxo-8-pyridin-3-yl-[1]benzofuro[3,2-b]pyridin-1-yl)phenyl]prop-2-enamide
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| Structure |
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| Formula |
C25H17N3O3
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| Molecular Weight |
407.429
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| Canonical SMILES |
C=CC(=O)Nc1ccc(cc1)-n1c2c(ccc1=O)oc1ccc(cc21)-c1cccnc1
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| InChI |
InChI=1S/C25H17N3O3/c1-2-23(29)27-18-6-8-19(9-7-18)28-24(30)12-11-22-25(28)20-14-16(5-10-21(20)31-22)17-4-3-13-26-15-17/h2-15H,1H2,(H,27,29)
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| InChIKey |
QHUBDROWGBQYIY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01308, Tyrosine-protein kinase BTK
Cell Viability or Cytotoxicity Assay