General Information of the Compound
| Compound ID |
CP0012958
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| Compound Name |
N-hydroxy-3-(1-naphthalen-1-yl-3,4-dihydro-1H-isoquinolin-2-yl)propanamide
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| Structure |
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| Formula |
C22H22N2O2
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| Molecular Weight |
346.43
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| Canonical SMILES |
ONC(=O)CCN1CCc2ccccc2C1c1cccc2ccccc12
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| InChI |
InChI=1S/C22H22N2O2/c25-21(23-26)13-15-24-14-12-17-7-2-4-10-19(17)22(24)20-11-5-8-16-6-1-3-9-18(16)20/h1-11,22,26H,12-15H2,(H,23,25)
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| InChIKey |
SCUQOPLYMBNYRP-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2