General Information of the Compound
Compound ID
CP0012945
Compound Name
3-[[(2R)-azetidin-2-yl]methoxy]-5-hex-1-ynylpyridine
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Structure
Formula
C15H20N2O
Molecular Weight
244.338
Canonical SMILES
CCCCC#Cc1cncc(OC[C@H]2CCN2)c1
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InChI
InChI=1S/C15H20N2O/c1-2-3-4-5-6-13-9-15(11-16-10-13)18-12-14-7-8-17-14/h9-11,14,17H,2-4,7-8,12H2,1H3/t14-/m1/s1
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InChIKey
VXRANFSOUCNARC-CQSZACIVSA-N
Physicochemical Property
logP
2.364
Rotatable Bonds
5
Heavy Atom Count
18
Polar Areas
34.15
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
18

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71584936
SID: 163637146
ChEMBL ID
CHEMBL3289072
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 13000 nM
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