General Information of the Compound
Compound ID
CP0001661
Compound Name
2-spiro[1,4-dihydroimidazole-5,3'-1-azabicyclo[2.2.2]octane]-2-yl-1-benzofuran-3-amine
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Structure
Formula
C17H20N4O
Molecular Weight
296.374
Canonical SMILES
Nc1c(oc2ccccc12)C1=NC2(CN1)CN1CCC2CC1
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InChI
InChI=1S/C17H20N4O/c18-14-12-3-1-2-4-13(12)22-15(14)16-19-9-17(20-16)10-21-7-5-11(17)6-8-21/h1-4,11H,5-10,18H2,(H,19,20)
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InChIKey
DRTIPJHGTWRGMH-UHFFFAOYSA-N
Physicochemical Property
logP
1.8292
Rotatable Bonds
1
Heavy Atom Count
22
Polar Areas
66.79
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56930491
SID: 135629436
ChEMBL ID
CHEMBL1911862
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
EC50 = 1200 nM
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