General Information of the Compound
Compound ID
CP0000163
Compound Name
Ambien
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Synonyms
ZolpiMist
7K383OQI23
82626-48-0
Ambien
CHEBI:10125
CHEMBL911
DEA No 2783
Lorex
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
N,N,6-Trimethyl-2-p-tolylimidazo[1,2-a]pyridine-3-acetamide
N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
NCGC00095179-01
SL-800750
UNII-7K383OQI23
ZAFYATHCZYHLPB-UHFFFAOYSA-N
Zolpidem
Zolpidem (low-dose oral spray, middle-of-the-night awakenings)
Zolpidem (low-dose oral spray, middle-of-the-night awakenings), NovaDel
Zolpidem [INN:BAN]
Zolpidem tartrate
Zolpidemum
Zolpidemum [Latin]
[3H]zolpidem
zolpidem
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Structure
Formula
C19H21N3O
Molecular Weight
307.397
Canonical SMILES
CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
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InChI
InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3
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InChIKey
ZAFYATHCZYHLPB-UHFFFAOYSA-N
CAS
82626-48-0
Physicochemical Property
logP
3.24884
Rotatable Bonds
3
Heavy Atom Count
23
Polar Areas
37.61
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 5732
SID: 14874110
ChEMBL ID
CHEMBL911
DrugBank ID
DB00425
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05269, Gamma-aminobutyric acid receptor subunit alpha-2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 765 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Zolpidem )
Drug Name Zolpidem
Company NovaDel Pharma Inc
Indication
Insomnia
Approved
Insomnia
Phase 1
Target(s)
GABA(A) receptor alpha-1 (GABRA1)
 Target Info 
Modulator