General Information of the Cell Line
Cell Line ID
CL000768
Cell Line Name
AML-1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Disease
Childhood acute myeloid leukemia (NCIt: C9160)
Acute myeloid leukemia (ORDO: Orphanet_519)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
 Protein Info 
Compound ID Compound Name Compound Formula
CP0030740
 Compound Info 
1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea
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C29H32N6O4S
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0115223
 Compound Info 
4-[6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C30H40N6O5
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01010, Thymidylate synthase
 Protein Info 
Protein family and CMB statistics Related to the Cell Line