Brief Information of the Cell Line and Protein
Cell Line ID: CL000768 , AML-1
 Cell Line Info 
Category Cancer cell line
Organism
Homo sapiens (Human)
Protein ID: PT01010 , Thymidylate synthase
 Protein Info 
Gene Name TYMS
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P04818
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000768
 Cell Line Info 
 Protein ID: PT01010
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0046656
 Compound Info 
(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}phenyl)formamido]pentanedioic acid
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C24H23N5O6
  1
1
Ki = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401470
 Compound Info 
2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(10-methylfolate)
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C20H21N7O6
  1
1
Ki = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0068879
 Compound Info 
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
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C19H19N7O6
  1
1
Ki = 40000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS