General Information of the Cell Line
Cell Line ID
CL000739
Cell Line Name
U87.CD4.CCR5
Synonyms
U87/CD4/CCR5
U87.CD4-CCR5
U87 CD4+CCR5+
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_X630
Disease
Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03814, C-X-C chemokine receptor type 5
Compound ID Compound Name Compound Formula
CP0002124
4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1S,5S)-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-phenyl-propyl}-amide
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C29H41F2N5O
 1
1
IC50 = 4.672169 nM
   TI
   LI
   LO
   TS
CP0866103
1',1'',1''',1'''',1''''',1'''''',1''''''',1'''''''',1''''''''',1'''''''''',1''''''''''',1''''''''''''-(5,5',5'',5''',5'''',5'''''-(1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(4,4'-bipyridine-1,1'-diium-1',1-diyl))hexakis(methylene)hexakis(benzene-5,3,1-triyl))dodecakis(methylene)dodecakis(1-ethyl-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
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C324H318F252N42P42
 1
1
IC50 = 541.84066 nM
   TI
   LI
   LO
   TS
CP0852033
1',1'',1''',1'''',1''''',1'''''',1''''''',1'''''''',1''''''''',1'''''''''',1''''''''''',1''''''''''''-(5,5',5'',5''',5'''',5'''''-(1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4',4''-bipyridine-1,1'-diium-1',1'-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(4'',4'''-bipyridine-1,1'-diium-1'',1'-diyl))hexakis(methylene)hexakis(benzene-5,3,1-triyl))dodecakis(methylene)dodecakis(1-(3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propyl)-4'''''''',4'''''''''-bipyridine-1,1'-diium)hexafluorophosphate (V)
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C396H390F252N66O24P42
 1
1
IC50 = 1749.51699 nM
   TI
   LI
   LO
   TS
CP0866102
1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(1-(3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propyl)-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
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C174H174F108N30O12P18
 1
1
IC50 = 1868.113042 nM
   TI
   LI
   LO
   TS
CP0852034
1',1'',1''',1'''',1''''',1'''''',1''''''',1''''''''-(5,5',5'',5'''-(1',1'',1''',1''''-(5,5'-(4,4'-bipyridine-1,1'-diium-1,1'-diyl)bis(benzene-5,3,1-triyl))tetrakis(methylene)tetrakis(4',4''-bipyridine-1,1'-diium-1',1'-diyl))tetrakis(methylene)tetrakis(benzene-5,3,1-triyl))octakis(methylene)octakis(1-(3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propyl)-4',4''-bipyridine-1,1'-diium)hexafluorophosphate (V)
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C246H242F156N42O16P26
 1
1
IC50 = 3661.067111 nM
   TI
   LI
   LO
   TS
CP0860688
1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(1-ethyl-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
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C138H138F108N18P18
 1
1
IC50 = 4860.392524 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line