General Information of the Cell Line
Cell Line ID
CL000653
Cell Line Name
Chem-4
Synonyms
ChemiSCREEN Chem-4
Wild-type control Chem-4 cell line
ChemiSCREEN Chem-4 parental cell line
Chem4
Category
Undefined cell line type
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_GS44
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00834, Cannabinoid receptor 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0385856
 Compound Info 
6-cyclopropyl-1-(2,4-dichlorophenyl)-N-[(1S,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-4H-indeno[1,2-c]pyrazole-3-carboxamide
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C30H31Cl2N3O
  1
1
IC50 = 26.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0428364
 Compound Info 
N-(1-adamantyl)-6-cyclopropyl-1-(2,4-dichlorophenyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide
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C30H29Cl2N3O
  1
1
IC50 = 50.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392586
 Compound Info 
6-cyclopropyl-1-(2,4-dichlorophenyl)-N-[(1S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]-4H-indeno[1,2-c]pyrazole-3-carboxamide
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C30H31Cl2N3O
  1
1
IC50 = 80.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0415780
 Compound Info 
5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrrole-3-carboxamide
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C30H35ClN2O
  1
1
IC50 = 171.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0428366
 Compound Info 
6-cyclopropyl-1-(2,4-dichlorophenyl)-N-piperidin-1-yl-4H-indeno[1,2-c]pyrazole-3-carboxamide
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C25H24Cl2N4O
  1
1
IC50 = 294.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422480
 Compound Info 
5-(4-chloro-3-methylphenyl)-N-[[(1S,2R)-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]methyl]-1-[(4-methylphenyl)methyl]pyrrole-3-carboxamide
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C30H35ClN2O
  1
1
IC50 = 1816 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line