General Information of the Cell Line
Cell Line ID
CL000264
Cell Line Name
RD
Synonyms
R D
RD-2
RD 2
130T
130-T
130 T
TE-32
TE 32
TE32
TE 32.T
Te 32.T
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1649
Tissue Information
Pelvis
Disease
Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00962, Glycogen synthase kinase-3 beta
 Protein Info 
Compound ID Compound Name Compound Formula
CP0340584
 Compound Info 
N-(4-ethoxypyridin-3-yl)-2-(4-fluorophenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C20H16FN5O2
  1
1
EC50 = 1.5 nM
 Bioactivity Info 
   TI
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CP0143204
 Compound Info 
2-(4-fluorophenyl)-N-(4-methoxypyridin-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C19H14FN5O2
  1
1
EC50 = 9 nM
 Bioactivity Info 
   TI
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CP0143205
 Compound Info 
N-(4-ethoxypyridin-3-yl)-2-(3-methoxyphenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H19N5O3
  1
1
EC50 = 10 nM
 Bioactivity Info 
   TI
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CP0338344
 Compound Info 
N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-thiophen-3-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H21N5O3S2
  1
1
EC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0361955
 Compound Info 
2-(3-chlorophenyl)-N-(4-methoxypyridin-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C19H14ClN5O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
   TI
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CP0537261
 Compound Info 
N-(4-ethoxypyridin-3-yl)-2-pyridin-3-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C19H16N6O2
  1
1
EC50 = 10 nM
 Bioactivity Info 
   TI
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CP0076277
 Compound Info 
2-(2,4-difluorophenyl)-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C23H20F2N4O4S
  2
1
EC50 = 13 nM
 Bioactivity Info 
   TI
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2
EC50 = 580 nM
 Bioactivity Info 
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CP0361793
 Compound Info 
N-(4-methoxypyridin-3-yl)-2-pyridin-4-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C18H14N6O2
  1
1
EC50 = 20 nM
 Bioactivity Info 
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CP0143242
 Compound Info 
2-[4-(diethylamino)phenyl]-N-(4-methylpyridin-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H24N6O
  1
1
EC50 = 23 nM
 Bioactivity Info 
   TI
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CP0244881
 Compound Info 
N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-(4-fluorophenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H22FN5O3S
  1
1
EC50 = 31 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0093944
 Compound Info 
N-[3-(4,5-dichloroimidazol-1-yl)propyl]-7-hydroxy-2-thiophen-2-yl-1H-benzimidazole-4-carboxamide
   Show/Hide
C18H15Cl2N5O2S
  1
1
EC50 = 34 nM
 Bioactivity Info 
   TI
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CP0036209
 Compound Info 
N-[3-(4,5-dichloroimidazol-1-yl)propyl]-2-(furan-2-yl)-7-hydroxy-1H-benzimidazole-4-carboxamide
   Show/Hide
C18H15Cl2N5O3
  2
1
EC50 = 40 nM
 Bioactivity Info 
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2
EC50 = 50 nM
 Bioactivity Info 
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CP0340583
 Compound Info 
N-(4-methylpyridin-3-yl)-2-(3-phenylpyrrolidin-1-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H22N6O
  1
1
EC50 = 40 nM
 Bioactivity Info 
   TI
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CP0271246
 Compound Info 
N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-thiophen-2-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H21N5O3S2
  1
1
EC50 = 50 nM
 Bioactivity Info 
   TI
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CP0317647
 Compound Info 
N-[2-[4-(dimethylsulfamoylamino)phenyl]ethyl]-2-thiophen-3-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H22N6O3S2
  1
1
EC50 = 56 nM
 Bioactivity Info 
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CP0143258
 Compound Info 
N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-phenyl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H23N5O3S
  1
1
EC50 = 62 nM
 Bioactivity Info 
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CP0126239
 Compound Info 
2-[3-[3-[[2-(4-chlorophenyl)-7-hydroxy-1H-benzimidazole-4-carbonyl]amino]propyl]phenoxy]acetic acid
   Show/Hide
C25H22ClN3O5
  2
1
EC50 = 80 nM
 Bioactivity Info 
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2
EC50 = 250 nM
 Bioactivity Info 
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CP0257762
 Compound Info 
2-(4-fluorophenyl)-N-(6-methylpyridin-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C19H14FN5O
  1
1
EC50 = 80 nM
 Bioactivity Info 
   TI
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CP0298089
 Compound Info 
2-(4-fluorophenyl)-7-hydroxy-N-[2-[4-[(4-methylphenyl)sulfonylamino]phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C29H25FN4O4S
  1
1
EC50 = 95 nM
 Bioactivity Info 
   TI
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CP0076276
 Compound Info 
2-(3-chloro-4-fluorophenyl)-7-hydroxy-N-(3-imidazol-1-ylpropyl)-1H-benzimidazole-4-carboxamide
   Show/Hide
C20H17ClFN5O2
  2
1
EC50 = 100 nM
 Bioactivity Info 
   TI
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2
EC50 = 490 nM
 Bioactivity Info 
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CP0075040
 Compound Info 
N-[3-(4,5-dichloroimidazol-1-yl)propyl]-2-(2,4-dichlorophenyl)-7-hydroxy-1H-benzimidazole-4-carboxamide
   Show/Hide
C20H15Cl4N5O2
  2
1
EC50 = 110 nM
 Bioactivity Info 
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2
EC50 = 170 nM
 Bioactivity Info 
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CP0036208
 Compound Info 
2-(4-chlorophenyl)-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C23H21ClN4O4S
  1
1
EC50 = 120 nM
 Bioactivity Info 
   TI
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CP0163747
 Compound Info 
2-(4-fluorophenyl)-N-pyridin-3-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C18H12FN5O
  1
1
EC50 = 130 nM
 Bioactivity Info 
   TI
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CP0163748
 Compound Info 
N-[2-[4-(methanesulfonamido)phenyl]ethyl]-2-thiophen-2-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C20H19N5O3S2
  1
1
EC50 = 150 nM
 Bioactivity Info 
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CP0498261
 Compound Info 
2-(4-fluorophenyl)-N-[2-(3-hydroxyphenyl)ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H17FN4O2
  1
1
EC50 = 150 nM
 Bioactivity Info 
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CP0295493
 Compound Info 
2-(furan-3-yl)-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C20H19N5O4S
  1
1
EC50 = 180 nM
 Bioactivity Info 
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CP0566439
 Compound Info 
2-(4-fluorophenyl)-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C22H20FN5O3S
  1
1
EC50 = 190 nM
 Bioactivity Info 
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CP0340591
 Compound Info 
N-[2-[4-(dimethylsulfamoylamino)phenyl]ethyl]-2-(4-fluorophenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H23FN6O3S
  1
1
EC50 = 210 nM
 Bioactivity Info 
   TI
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CP0308841
 Compound Info 
2-(2-chloro-4-fluorophenyl)-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C23H20ClFN4O4S
  1
1
EC50 = 230 nM
 Bioactivity Info 
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CP0273363
 Compound Info 
2-(2,4-dichlorophenyl)-7-hydroxy-N-(3-imidazol-1-ylpropyl)-1H-benzimidazole-4-carboxamide
   Show/Hide
C20H17Cl2N5O2
  1
1
EC50 = 240 nM
 Bioactivity Info 
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CP0338345
 Compound Info 
N-pyridin-3-yl-2-thiophen-3-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C16H11N5OS
  1
1
EC50 = 240 nM
 Bioactivity Info 
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CP0338347
 Compound Info 
N-[3-(6-chloropyridin-3-yl)propyl]-2-(4-fluorophenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H17ClFN5O
  1
1
EC50 = 250 nM
 Bioactivity Info 
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CP0333341
 Compound Info 
N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-(furan-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C21H21N5O4S
  1
1
EC50 = 290 nM
 Bioactivity Info 
   TI
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CP0426221
 Compound Info 
2-(2,4-difluorophenyl)-N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C23H21F2N5O3S
  1
1
EC50 = 290 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0340592
 Compound Info 
2-(4-chlorophenyl)-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C22H20ClN5O3S
  1
1
EC50 = 300 nM
 Bioactivity Info 
   TI
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   LO
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CP0432229
 Compound Info 
2-(4-fluorophenyl)-N-[2-(6-fluoropyridin-3-yl)ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C20H15F2N5O
  1
1
EC50 = 300 nM
 Bioactivity Info 
   TI
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CP0306770
 Compound Info 
7-hydroxy-N-[3-(4-methylimidazol-1-yl)propyl]-2-thiophen-2-yl-1H-benzimidazole-4-carboxamide
   Show/Hide
C19H19N5O2S
  1
1
EC50 = 310 nM
 Bioactivity Info 
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   LO
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CP0244882
 Compound Info 
N-[2-(2-chloropyridin-3-yl)ethyl]-2-(furan-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
   Show/Hide
C18H14ClN5O2
  1
1
EC50 = 310 nM
 Bioactivity Info 
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CP0077926
 Compound Info 
N-[2-[4-(4-ethylpiperazine-1-carbonyl)phenyl]ethyl]-7-hydroxy-2-thiophen-2-yl-1H-benzimidazole-4-carboxamide
   Show/Hide
C27H29N5O3S
  1
1
EC50 = 400 nM
 Bioactivity Info 
   TI
   LI
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CP0267929
 Compound Info 
2-(4-fluorophenyl)-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C23H21FN4O4S
  1
1
EC50 = 400 nM
 Bioactivity Info 
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CP0308840
 Compound Info 
2-cyclopentyl-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C22H26N4O4S
  1
1
EC50 = 2700 nM
 Bioactivity Info 
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CP0275741
 Compound Info 
2-benzyl-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C24H24N4O4S
  1
1
EC50 = 3900 nM
 Bioactivity Info 
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CP0275742
 Compound Info 
2-cyclopropyl-7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-benzimidazole-4-carboxamide
   Show/Hide
C20H22N4O4S
  1
1
EC50 = 4800 nM
 Bioactivity Info 
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CP0205237
 Compound Info 
7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-2-methyl-1H-benzimidazole-4-carboxamide
   Show/Hide
C18H20N4O4S
  1
1
EC50 = 21000 nM
 Bioactivity Info 
   TI
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CP0308842
 Compound Info 
7-hydroxy-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-2-pyridin-4-yl-1H-benzimidazole-4-carboxamide
   Show/Hide
C22H21N5O4S
  1
1
EC50 = 25000 nM
 Bioactivity Info 
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Protein ID: PT06427, Genome polyprotein
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0218578
 Compound Info 
2-[[2-(2-methoxy-4-morpholin-4-ylanilino)-5-(trifluoromethyl)pyridin-4-yl]amino]-N-methylbenzamide
   Show/Hide
 C25H26F3N5O3  1
1
IC50 = 1220 nM
   TI
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CP0362936
 Compound Info 
BCX-4430
   Show/Hide
 C11H15N5O3  1
1
CC50 > 89000 nM
   TI
   LI
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CP0391895
 Compound Info 
4-[5-[5-[[(1E)-1-ethoxyimino-2,3-dihydroinden-5-yl]oxy]pentyl]-1,1-dioxo-1,2,5-thiadiazolidin-2-yl]pyridin-2-amine
   Show/Hide
 C23H31N5O4S  1
1
CC50 = 42000 nM
   TI
   LI
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CP0445795
 Compound Info 
N-[5-[2-(2-hydroxyethylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
   Show/Hide
 C14H20N4O2S2  2
1
CC50 = 41200 nM
   TI
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2
CC50 > 293000 nM
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CP0445797
 Compound Info 
2-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]acetic acid
   Show/Hide
 C14H18N4O3S2  1
1
CC50 > 282000 nM
   TI
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CP0458180
 Compound Info 
N-[5-[2-[cyclohexyl(methyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
   Show/Hide
 C16H22N4OS2  1
1
CC50 = 19400 nM
   TI
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CP0517645
 Compound Info 
3-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]benzoic acid
   Show/Hide
 C19H20N4O3S2  1
1
CC50 = 36300 nM
   TI
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pelvis)
Cell Line Name Organism Disease
TE 671
 Cell Line Info 
Homo sapiens (Human) Embryonal rhabdomyosarcoma