| Compound ID |
Compound Name |
Compound Formula |
|
CP0002393
|
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
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|
C16H20N6O
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0165499
|
3-[2-[5-methyl-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile
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|
C24H25N5O5
|
1
|
| 1 |
IC50 = 200.3 nM
|
|
|
|
CP0145368
|
3-[2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile
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|
C25H26N6O3
|
1
|
| 1 |
IC50 = 543.3 nM
|
|
|
|
CP0326425
|
3-[2-[2-(3,5-difluoro-4-morpholin-4-ylanilino)-5-methylpyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile
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|
C25H24F2N6O3
|
1
|
| 1 |
IC50 = 622.7 nM
|
|
|
|
CP0306526
|
N-(3,5-difluoro-4-morpholin-4-ylphenyl)-5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)pyrimidin-2-amine
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|
C23H25F2N5O4S
|
1
|
| 1 |
IC50 = 1096 nM
|
|
|
|
CP0089651
|
(R)-3-(6-(1-(4-fluorophenyl)propylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C19H18FN7
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0207126
|
(R)-3-(6-(1-(4-fluorophenyl)butylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C20H20FN7
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0291008
|
3-(6-(2-(4-fluorophenyl)pyrrolidin-1-yl)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C20H18FN7
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0308346
|
(R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C18H16FN7
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0252996
|
(R)-3-(6-(1-(4-fluorophenyl)-2-methylpropylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C20H20FN7
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0280668
|
(R)-3-(6-(1-(4-chlorophenyl)ethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C18H16ClN7
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0070994
|
(S)-3-(6-(1-phenylethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C18H17N7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0283874
|
(R)-3-(6-(2,3-dihydro-1H-inden-1-ylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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|
C19H17N7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
