Brief Information of the Cell Line and Protein
Cell Line ID: CL001022 , HEK293EM
 Cell Line Info 
Synonyms
HEK-EM293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04434 , Lutropin-choriogonadotropic hormone receptor
 Protein Info 
Gene Name LHCGR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P22888
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL001022
 Cell Line Info 
 Protein ID: PT04434
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0115536
 Compound Info 
5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C19H22N4O2S2
  1
1
EC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381565
 Compound Info 
5-amino-N-tert-butyl-4-(3-methoxyphenyl)-N-methyl-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C20H24N4O2S2
  1
1
EC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0505626
 Compound Info 
5-amino-N-tert-butyl-4-(2,3-dimethoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C20H24N4O3S2
  1
1
EC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0408155
 Compound Info 
tert-butyl 5-amino-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxylate
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C19H21N3O3S2
  1
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381560
 Compound Info 
5-amino-N-tert-butyl-4-(3-fluorophenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C18H19FN4OS2
  1
1
EC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0408080
 Compound Info 
5-amino-N-tert-butyl-4-(2-fluoro-3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C19H21FN4O2S2
  1
1
EC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0390551
 Compound Info 
5-amino-N-tert-butyl-4-(3-hydroxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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C18H20N4O2S2
  1
1
EC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS