Brief Information of the Cell Line and Protein
Cell Line ID: CL000901 , 661W
Synonyms
661w
661 W
Category Transformed cell line
Organism
Mus musculus (Mouse)
Protein ID: PT00941 , 5-hydroxytryptamine receptor 7
Gene Name HTR7
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P34969
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000901  Protein ID: PT00941
 
Compound ID Compound Name Compound Formula
CP0391130
(3aS,9bS)-3,3a-dimethyl-5-phenyl-1,2,4,9b-tetrahydropyrrolo[2,3-c]quinoline
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C19H22N2
 1
1
Ki = 2.692 nM
   TI
   LI
   LO
   TS
CP0426378
(3aS,9bS)-3,3a-dimethyl-6-phenyl-1,2,4,9b-tetrahydrochromeno[3,4-b]pyrrole
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C19H21NO
 1
1
Ki = 19.95 nM
   TI
   LI
   LO
   TS
CP0426383
(3aS,9bS)-3a-methyl-6-phenyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C18H19NO
 1
1
Ki = 23.44 nM
   TI
   LI
   LO
   TS
CP0426380
(3aS,9bS)-8-methoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C13H17NO2
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0426405
(3aS,9bS)-3a,8-dimethyl-5-(4-methylphenyl)-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
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C20H24N2
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0432125
(3aS,9bS)-8-bromo-5-(4-bromophenyl)-3a-methyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
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C18H18Br2N2
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0426384
(3aS,9bS)-6-bromo-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C12H14BrNO
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0426421
(1S,2S)-1-ethyl-2-methyl-1,3-dihydrobenzo[f]chromen-2-amine
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C16H19NO
 1
1
Ki = 691.83 nM
   TI
   LI
   LO
   TS
CP0411059
(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
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C18H22N2
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0426385
(3aS,9bS)-3a-methyl-8-phenyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C18H19NO
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0455600
(3S,4S)-4-ethyl-3-methyl-2,4-dihydrobenzo[h]chromen-3-amine
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C16H19NO
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0391154
(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C14H19NO3
 1
1
Ki = 1258.93 nM
   TI
   LI
   LO
   TS
CP0426382
(3aS,9bS)-3a,7,9-trimethyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C14H19NO
 1
1
Ki = 1258.93 nM
   TI
   LI
   LO
   TS
CP0391120
(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
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C14H21NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391121
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
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C13H19NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS