| Compound ID |
Compound Name |
Compound Formula |
|
CP0436262
|
7-[4-(4-phenylpiperazin-1-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
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|
C23H29N3O2
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0518814
|
UNC10108010
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|
C25H30N4O4
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0453632
|
7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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|
C24H31N3O3
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
EC50 = 0.6 nM
|
|
|
|
CP0531455
|
UNC10108018
Show/Hide
|
C24H30N4O4
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0392345
|
7-[4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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|
C23H28FN3O2
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0436260
|
7-[4-[4-(2-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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|
C25H33N3O3
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0453634
|
2-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]benzonitrile
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|
C24H28N4O2
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0292498
|
UNC10108019
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|
C25H29N3O4
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0396578
|
1,6-Dimethylcabergoline
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|
C25H37N5O2
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0318171
|
UNC10108017
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|
C25H31N3O4
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0292499
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
Show/Hide
|
C23H28Cl2N4O2
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
EC50 = 3.3 nM
|
|
|
|
CP0436263
|
7-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0436264
|
7-[4-[4-(2,3-dichlorophenyl)piperidin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H28Cl2N2O2
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0488175
|
7-[4-[4-(2-chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0078330
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H29Cl2N3O2
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 3.3 nM
|
|
|
|
CP0097331
|
UNC10107966
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0107094
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-1H-quinolin-2-one
Show/Hide
|
C24H27Cl2N3O2
|
2
|
| 1 |
EC50 = 2.5 nM
|
|
|
| 2 |
EC50 = 2.8 nM
|
|
|
|
CP0514063
|
7-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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|
C24H28F3N3O2
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0516751
|
UNC10107954
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|
C25H31N3O3
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0346568
|
UNC10000003
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
|
CP0217007
|
7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
Show/Hide
|
C22H26Cl2N4O2
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0445308
|
7-[4-[4-(2-methylphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0392383
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-2H-isoquinolin-1-one
Show/Hide
|
C23H27Cl2N3O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
EC50 = 18 nM
|
|
|
|
CP0576919
|
UNC10107959
Show/Hide
|
C25H34N4O3
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0283546
|
UNC10107967
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0342612
|
UNC10107969
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0173602
|
UNC10107958
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0346569
|
UNC10107953
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0442857
|
UNC10107968
Show/Hide
|
C26H36N4O3
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0324453
|
UNC10107962
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0456743
|
7-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0518813
|
UNC10107955
Show/Hide
|
C24H32N4O3
|
1
|
| 1 |
EC50 = 6.1 nM
|
|
|
|
CP0188914
|
UNC10099984
Show/Hide
|
C24H29Cl2N3O2
|
1
|
| 1 |
EC50 = 6.2 nM
|
|
|
|
CP0283545
|
7-[3-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]propoxy]-3,4-dihydro-2H-isoquinolin-1-one
Show/Hide
|
C23H27Cl2N3O2
|
2
|
| 1 |
EC50 = 6.3 nM
|
|
|
| 2 |
EC50 = 8 nM
|
|
|
|
CP0445310
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1H-quinolin-2-one
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0531454
|
UNC10108005
Show/Hide
|
C21H24Cl2N4O2
|
1
|
| 1 |
EC50 = 8.5 nM
|
|
|
|
CP0516191
|
UNC10108049
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
EC50 = 9.2 nM
|
|
|
|
CP0499478
|
7-[4-[4-(3-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0318170
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1,3-dihydrobenzimidazol-2-one
Show/Hide
|
C21H24Cl2N4O2
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 65 nM
|
|
|
|
CP0402522
|
UNC10107957
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0392316
|
5-[4-[4-(2,3-dichlorophenyl)piperidin-1-yl]butoxy]-1,3-dihydrobenzimidazol-2-one
Show/Hide
|
C22H25Cl2N3O2
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
EC50 = 25 nM
|
|
|
|
CP0392320
|
7-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-3,4-dihydro-2H-isoquinolin-1-one
Show/Hide
|
C22H25Cl2N3O2
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
EC50 = 30 nM
|
|
|
|
CP0107095
|
5-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C22H25Cl2N3OS
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
EC50 = 25 nM
|
|
|
|
CP0117340
|
UNC10099988
Show/Hide
|
C20H22Cl2N4O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0283548
|
UNC10000011
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0283547
|
5-[3-[4-(2,3-dichlorophenyl)piperidin-1-yl]propoxy]-1,3-benzothiazole
Show/Hide
|
C21H22Cl2N2OS
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
|
CP0453633
|
7-[4-[4-(4-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0392318
|
7-[3-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]phenoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H25Cl2N3O2
|
2
|
| 1 |
EC50 = 58 nM
|
|
|
| 2 |
EC50 = 316 nM
|
|
|
|
CP0320773
|
6-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-1H-indazole
Show/Hide
|
C20H22Cl2N4O
|
2
|
| 1 |
EC50 = 59 nM
|
|
|
| 2 |
EC50 = 200 nM
|
|
|
|
CP0436261
|
5-[3-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]propoxy]-1,3-benzothiazole
Show/Hide
|
C21H23Cl2N3OS
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0292497
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C21H23Cl2N3OS
|
2
|
| 1 |
EC50 = 63 nM
|
|
|
| 2 |
EC50 = 64 nM
|
|
|
|
CP0329148
|
UNC10099985
Show/Hide
|
C24H28Cl2N2O2
|
1
|
| 1 |
EC50 = 64 nM
|
|
|
|
CP0078329
|
5-[4-[4-(2,3-dichlorophenyl)piperidin-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C22H24Cl2N2OS
|
2
|
| 1 |
EC50 = 79 nM
|
|
|
| 2 |
EC50 = 82 nM
|
|
|
|
CP0486943
|
7-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C22H25Cl2N3O2
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0187462
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1H-indazole
Show/Hide
|
C21H24Cl2N4O
|
2
|
| 1 |
EC50 = 92 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
|
CP0443660
|
5-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-1,3-benzothiazole
Show/Hide
|
C20H21Cl2N3OS
|
2
|
| 1 |
EC50 = 107 nM
|
|
|
| 2 |
EC50 = 126 nM
|
|
|
|
CP0188931
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-ynoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H23Cl2N3O2
|
2
|
| 1 |
EC50 = 199 nM
|
|
|
| 2 |
EC50 = 610 nM
|
|
|
|
CP0392317
|
7-[4-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]phenoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H25Cl2N3O2
|
2
|
| 1 |
EC50 = 399 nM
|
|
|
| 2 |
EC50 = 501 nM
|
|
|
|
CP0445307
|
7-[[(1R,2S)-2-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]cyclopropyl]oxymethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H27Cl2N3O2
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0453630
|
CHEMBL2165128
Show/Hide
|
C27H33Cl2N3O2
|
1
|
| 1 |
EC50 = 1580 nM
|
|
|
|
CP0516189
|
UNC10000007
Show/Hide
|
C27H33Cl2N3O2
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
