| Compound ID |
Compound Name |
Compound Formula |
|
CP0054000
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(thiophen-2-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C22H26BrNS
|
3
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 32000 nM
|
|
|
| 3 |
IC50 = 38000 nM
|
|
|
|
CP0129037
|
(1R,8S,10S)-3-(3,4-dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C23H25Cl2N
|
2
|
| 1 |
IC50 = 9000 nM
|
|
|
| 2 |
IC50 = 64000 nM
|
|
|
|
CP0364998
|
3-[[(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trien-9-yl]methyl]-5-methyl-1,2-oxazole
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|
C22H27BrN2O
|
2
|
| 1 |
IC50 = 12000 nM
|
|
|
| 2 |
IC50 = 48000 nM
|
|
|
|
CP0098703
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C22H32BrN
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0066079
|
(1R,8S,10S)-3,6-dibromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C17H21Br2N
|
2
|
| 1 |
IC50 = 25000 nM
|
|
|
| 2 |
IC50 = 40000 nM
|
|
|
|
CP0305214
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-methylsulfonyl-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C18H24BrNO2S
|
2
|
| 1 |
IC50 = 27000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0066364
|
(1R,8S,10S)-9-[(3-fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C24H28FN
|
2
|
| 1 |
IC50 = 30000 nM
|
|
|
| 2 |
IC50 = 68000 nM
|
|
|
|
CP0066363
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylpropyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C17H24BrN
|
2
|
| 1 |
IC50 = 31000 nM
|
|
|
| 2 |
IC50 = 78000 nM
|
|
|
|
CP0053883
|
(1R,8S,10S)-9-(1,3-benzodioxol-5-ylmethyl)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C25H28BrNO2
|
2
|
| 1 |
IC50 = 40000 nM
|
|
|
| 2 |
IC50 = 88000 nM
|
|
|
|
CP0066077
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C17H22BrN
|
2
|
| 1 |
IC50 = 40000 nM
|
|
|
| 2 |
IC50 = 46000 nM
|
|
|
|
CP0230785
|
(1R,8S,10S)-3-bromo-9-[(3-fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C24H27BrFN
|
2
|
| 1 |
IC50 = 51000 nM
|
|
|
| 2 |
IC50 = 68000 nM
|
|
|
|
CP0048791
|
(1R,8S,10S)-3-(3,4-dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C28H35Cl2N
|
2
|
| 1 |
IC50 = 79000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0048790
|
(1R,8S,10S)-3-bromo-9-(4-fluorophenyl)sulfonyl-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C23H25BrFNO2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0385229
|
(1R,8S,10S)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(quinolin-4-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C27H29BrN2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0048792
|
(1R,8S,10S)-3-bromo-9-(1H-indol-3-ylmethyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene
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|
C26H29BrN2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0053885
|
(1R,8S,10S)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C17H23N
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0142521
|
(1R,8S,10S)-9-(1,3-benzodioxol-5-ylmethyl)-3-(3,4-dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene
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|
C31H31Cl2NO2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
