Brief Information of the Cell Line and Protein
Cell Line ID: CL000880 , COS
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT02528 , Sodium- and chloride-dependent GABA transporter 1
Gene Name SLC6A1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P30531
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000880  Protein ID: PT02528
 
Compound ID Compound Name Compound Formula
CP0037615
1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid
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C22H25NO2
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0221365
(R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperidine-3-carboxylic acid hydrochloride
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C20H25NO2S2
 5
1
IC50 = 154.88 nM
   TI
   LI
   LO
   TS
2
Kd = 40.5 nM
   TI
   LI
   LO
   TS
3
Kd = 146.8 nM
   TI
   LI
   LO
   TS
4
Km = 19700 nM
   TI
   LI
   LO
   TS
5
Km = 29400 nM
   TI
   LI
   LO
   TS
CP0000066
4-amino-n-[2,3-3H]butyric acid
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C4H9NO2
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0059522
(R)-Piperidine-3-carboxylic acid
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C6H11NO2
 1
1
IC50 = 5960 nM
   TI
   LI
   LO
   TS
CP0171598
(RS)-nipecotic acid
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C6H11NO2
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0047120
1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydrochloride
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C6H9NO2
 1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0427513
(3R,5S)-5-[[(2E)-2-[(5-naphthalen-1-ylfuran-2-yl)methylidene]hydrazinyl]methyl]piperidine-3-carboxylic acid
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C22H23N3O3
 5
1
IC50 = 42657.95 nM
   TI
   LI
   LO
   TS
2
Kd = 56 nM
   TI
   LI
   LO
   TS
3
Kd = 111.9 nM
   TI
   LI
   LO
   TS
4
Km = 5700 nM
   TI
   LI
   LO
   TS
5
Km = 10100 nM
   TI
   LI
   LO
   TS
CP0427519
(3R,5S)-5-[[(2E)-2-[[5-[3,5-bis(trifluoromethyl)phenyl]furan-2-yl]methylidene]hydrazinyl]methyl]piperidine-3-carboxylic acid
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C20H19F6N3O3
 4
1
Kd = 57.7 nM
   TI
   LI
   LO
   TS
2
Kd = 154.2 nM
   TI
   LI
   LO
   TS
3
Km = 5100 nM
   TI
   LI
   LO
   TS
4
Km = 8200 nM
   TI
   LI
   LO
   TS