Brief Information of the Cell Line and Protein
Cell Line ID: CL000880 , COS
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01410 , Substance-P receptor
Gene Name TACR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25103
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000880  Protein ID: PT01410
 
Compound ID Compound Name Compound Formula
CP0049105
(SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
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C63H98N18O13S
 2
1
IC50 = 0.9 nM
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2
IC50 = 1.1 nM
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CP0380180
(4S,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-37-amino-34-(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-19-[(4-fluorophenyl)methyl]-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
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C74H92FN15O17S2
 2
1
IC50 = 900 nM
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2
IC50 = 9600 nM
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CP0373262
(4S,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-37-[[(2S)-2-[(2-aminoacetyl)amino]propanoyl]amino]-34-(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-19-[(4-fluorophenyl)methyl]-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
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C79H100FN17O19S2
 2
1
IC50 = 950 nM
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2
IC50 = 6100 nM
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CP0898983
6-N1N-(1-formylethyl)-2-aminoacetamide9-(4-aminobutyl)-15,18,30-tribenzyl-12-carbamoylmethyl-27,33-di(1-hydroxyethyl)-36-hydroxymethyl-7,10,13,16,19,22,25,28,31,34,37-undecaoxo-3,4-dithia-8,11,14,17,20,23,26,29,32,35,38-undecaazacyclooctatriacontane-1-carboxylic acid21-L-2-amino-3-(1H-3-indolyl)propanal24-4-fluoro-1-methylbenzene
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C79H100FN17O19S2
 2
1
IC50 = 2700 nM
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2
IC50 = 8200 nM
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