Brief Information of the Cell Line and Protein
Cell Line ID: CL000880 , COS
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01339 , Alpha-1A adrenergic receptor
Gene Name ADRA1A
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P43140
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000880  Protein ID: PT01339
 
Compound ID Compound Name Compound Formula
CP0049709
2-(4-Furan-2-yl-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine
   Show/Hide
C18H21N5O3
 1
1
Ki = 0.72 nM
   TI
   LI
   LO
   TS
CP0110274
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-3,3-diphenyl-propan-1-one
   Show/Hide
C29H31N5O3
 1
1
Ki = 1.48 nM
   TI
   LI
   LO
   TS
CP0096797
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-4-phenyl-butane-1,4-dione
   Show/Hide
C24H27N5O4
 1
1
Ki = 5.68 nM
   TI
   LI
   LO
   TS
CP0049357
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-ethanone
   Show/Hide
C26H33N5O5
 1
1
Ki = 7.5 nM
   TI
   LI
   LO
   TS
CP0122632
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-3-phenyl-propane-1,3-dione
   Show/Hide
C23H25N5O4
 1
1
Ki = 10.99 nM
   TI
   LI
   LO
   TS
CP0122703
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-methoxy-phenoxy)-ethanone
   Show/Hide
C23H27N5O5
 1
1
Ki = 18.95 nM
   TI
   LI
   LO
   TS
CP0358354
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2,6-dimethoxy-phenoxy)-ethanone
   Show/Hide
C24H29N5O6
 1
1
Ki = 36.2 nM
   TI
   LI
   LO
   TS
CP0270867
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-propan-1-one
   Show/Hide
C27H35N5O5
 1
1
Ki = 155.6 nM
   TI
   LI
   LO
   TS