Brief Information of the Cell Line and Protein
Cell Line ID: CL000880 , COS
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01005 , D(2) dopamine receptor
Gene Name DRD2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P14416
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000880  Protein ID: PT01005
 
Compound ID Compound Name Compound Formula
CP0003324
1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine
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C20H21ClN2
 1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0005956
1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-piperazine
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C19H19ClN2O
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0008953
1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-piperazine
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C19H19ClN2O
 1
1
Ki = 8.7 nM
   TI
   LI
   LO
   TS
CP0010829
1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine
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C19H20N2O
 1
1
Ki = 21 nM
   TI
   LI
   LO
   TS
CP0076121
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
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C18H18ClN3O
 1
1
Ki = 21 nM
   TI
   LI
   LO
   TS
CP0005197
1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-piperazine
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C21H22N2
 1
1
Ki = 57 nM
   TI
   LI
   LO
   TS
CP0183655
1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-piperazine
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C21H24N2
 1
1
Ki = 94 nM
   TI
   LI
   LO
   TS
CP0005613
8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
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C18H18ClN3O
 1
1
Ki = 150 nM
   TI
   LI
   LO
   TS
CP0011263
1-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine
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C23H26N2
 1
1
Ki = 290 nM
   TI
   LI
   LO
   TS
CP0002406
1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine
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C20H21ClN2
 1
1
Ki = 520 nM
   TI
   LI
   LO
   TS
CP0000272
1-(2-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine
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C23H25ClN2
 1
1
Ki = 690 nM
   TI
   LI
   LO
   TS
CP0004912
1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10-yl]-4-methyl-piperazine
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C22H24N2
 1
1
Ki = 730 nM
   TI
   LI
   LO
   TS