Brief Information of the Cell Line and Protein
Cell Line ID: CL000764 , Bone marrow macrophage immortalized C57BL/6
Synonyms
C57BL/6
C57BL/6 Macrophage Cell Line
Category Transformed cell line
Organism
Mus musculus (Mouse)
Protein ID: PT03356 , NACHT, LRR and PYD domains-containing protein 3
Gene Name NLRP3
Organism Mus musculus, Mouse
Protein Classification Unclassified protein
Uniprot ID Q8R4B8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000764  Protein ID: PT03356
 
Compound ID Compound Name Compound Formula
CP0544998
(1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one
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C20H28O6
 1
1
IC50 = 810 nM
   TI
   LI
   LO
   TS
CP0544999
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]furan-2-carboxamide
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C23H20N2O6
 1
1
IC50 = 1230 nM
   TI
   LI
   LO
   TS
CP0578131
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]benzamide
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C25H22N2O5
 1
1
IC50 = 1560 nM
   TI
   LI
   LO
   TS
CP0574275
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]thiophene-2-carboxamide
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C23H20N2O5S
 1
1
IC50 = 2150 nM
   TI
   LI
   LO
   TS
CP0016251
3,4-Methylenedioxyb-Nitrostyrene
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C9H7NO4
 1
1
IC50 = 2310 nM
   TI
   LI
   LO
   TS
CP0570495
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]-4-fluorobenzamide
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C25H21FN2O5
 1
1
IC50 = 9340 nM
   TI
   LI
   LO
   TS
CP0544994
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]-4-methoxybenzamide
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C26H24N2O6
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0544996
(E)-N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]-3-phenylprop-2-enamide
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C27H24N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0544997
2-bromo-N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]benzamide
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C25H21BrN2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0570492
N-[4-[(E)-2-[3,5-dimethoxy-2-[(E)-2-nitroethenyl]phenyl]ethenyl]phenyl]naphthalene-2-carboxamide
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C29H24N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0542770
N-(3-hydroxyphenyl)-2-(1H-indol-6-yl)acetamide
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C16H14N2O2
 1
1
IC50 = 48980 nM
   TI
   LI
   LO
   TS