Brief Information of the Cell Line and Protein
Cell Line ID: CL000742 , FreeStyle 293-F
 Cell Line Info 
Synonyms
Freestyle-293F
FreeStyle 293F
Freestyle 293F
FreeStyle293-F
FreeStyle293F
FreeStyle 293
Freestyle 293
FreeStyle293
Freestyle HEK293F
293-F FreeStyle
FS-293F
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_D603
Protein ID: PT07046 , Serine palmitoyltransferase 2
 Protein Info 
Gene Name SPTLC2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O15270
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000742
 Cell Line Info 
 Protein ID: PT07046
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0182768
 Compound Info 
CHEBI:582124
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C21H39NO6
  1
1
IC50 = 0.13 nM
 Bioactivity Info 
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CP0521562
 Compound Info 
2-chloro-N-[(3S,4R)-1-(3,4-dimethoxybenzoyl)-3-phenylpiperidin-4-yl]benzamide
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C27H27ClN2O4
  1
1
IC50 = 0.36 nM
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CP0521561
 Compound Info 
N-[(7S)-4-(5,6-dimethoxypyridine-3-carbonyl)-1-propan-2-yl-6,7-dihydro-5H-pyrazolo[4,3-b]pyridin-7-yl]-2-(trifluoromethoxy)benzamide
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C25H26F3N5O5
  1
1
IC50 = 0.54 nM
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CP0550422
 Compound Info 
N-[(3S,4R)-1-(8-chloroquinoxaline-6-carbonyl)-3-phenylpiperidin-4-yl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide
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C26H22ClF3N6O2
  1
1
IC50 = 0.71 nM
 Bioactivity Info 
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CP0469391
 Compound Info 
N-[4-(5,6-dimethoxypyridine-3-carbonyl)-1-propan-2-yl-6,7-dihydro-5H-pyrazolo[4,3-b]pyridin-7-yl]-2-(trifluoromethoxy)benzamide
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C25H26F3N5O5
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
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CP0513244
 Compound Info 
2-chloro-N-[1-(3,4-dimethoxybenzoyl)-3-phenylpiperidin-4-yl]benzamide
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C27H27ClN2O4
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
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CP0456047
 Compound Info 
2-chloro-N-[(3R,4R)-1-(3,4-dimethoxybenzoyl)-3-phenylpiperidin-4-yl]benzamide
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C27H27ClN2O4
  1
1
IC50 = 5 nM
 Bioactivity Info 
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CP0521560
 Compound Info 
2-chloro-N-[7-chloro-1-(3,4-dimethoxybenzoyl)-3,4-dihydro-2H-quinolin-4-yl]benzamide
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C25H22Cl2N2O4
  1
1
IC50 = 5.1 nM
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CP0575023
 Compound Info 
2-chloro-N-[4-(3,4-dimethoxybenzoyl)-1-methyl-6,7-dihydro-5H-pyrazolo[4,3-b]pyridin-7-yl]benzamide
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C23H23ClN4O4
  1
1
IC50 = 7.7 nM
 Bioactivity Info 
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CP0550421
 Compound Info 
2-chloro-N-[(3R,4S)-1-(3,4-dimethoxybenzoyl)-3-phenylpiperidin-4-yl]benzamide
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C27H27ClN2O4
  1
1
IC50 = 220 nM
 Bioactivity Info 
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CP0567274
 Compound Info 
[7-chloro-4-(4-chloroanilino)-3,4-dihydro-2H-quinolin-1-yl]-(3,4-dimethoxyphenyl)methanone
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C24H22Cl2N2O3
  1
1
IC50 = 650 nM
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CP0575024
 Compound Info 
N-[(7R)-4-(5,6-dimethoxypyridine-3-carbonyl)-1-propan-2-yl-6,7-dihydro-5H-pyrazolo[4,3-b]pyridin-7-yl]-2-(trifluoromethoxy)benzamide
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C25H26F3N5O5
  1
1
IC50 = 2800 nM
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CP0469392
 Compound Info 
2-chloro-N-[(3S,4S)-1-(3,4-dimethoxybenzoyl)-3-phenylpiperidin-4-yl]benzamide
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C27H27ClN2O4
  1
1
IC50 = 3000 nM
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