Brief Information of the Cell Line and Protein
Cell Line ID: CL000524 , HEK293-FT
Synonyms
HEK-293FT
HEK 293FT
HEK-293-FT
HEK293FT
293-FT
293FT
FT-293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6911
Protein ID: PT01648 , Vasopressin V2 receptor
Gene Name AVPR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P30518
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000524  Protein ID: PT01648
 
Compound ID Compound Name Compound Formula
CP0405331
(2S)-2-(dimethylcarbamothioyl)-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]pyrrolidine-1-carboxamide
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C28H33N7O2S
 2
1
EC50 = 41 nM
   TI
   LI
   LO
   TS
2
EC50 = 660 nM
   TI
   LI
   LO
   TS
CP0117986
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C43H66N12O12S2
 2
1
EC50 = 210 nM
   TI
   LI
   LO
   TS
2
EC50 = 810 nM
   TI
   LI
   LO
   TS
CP0386874
CHEBI:59204
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C45H69N11O12S
 2
1
EC50 = 1100 nM
   TI
   LI
   LO
   TS
2
EC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0219136
4-[(3,5-dihydroxyphenyl)methyl]-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]piperazine-1-carboxamide
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C32H35N7O4
 1
1
EC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0194007
5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
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C19H19ClFN5O3
 2
1
IC50 = 1530 nM
   TI
   LI
   LO
   TS
2
IC50 = 2620 nM
   TI
   LI
   LO
   TS