Brief Information of the Cell Line and Protein
Cell Line ID: CL000475 , SK-N-BE(2)-C
Synonyms
SK-N-BE(2)C
SK-N-BE-2c
SK-N-BE2(c)
SK-N-BE(2C)
SK-N-BE(2c)
SK-N-BE2C
SK_N_BE2C
SKNBE2C
SKNBE(2c)
BE(2)-C
BE(2)C
Be(2)C
BE2-C
BE2_C
Be2-C
BE2C
Be2C
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0529
Protein ID: PT02185 , Sodium- and chloride-dependent glycine transporter 1
Gene Name SLC6A9
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P48067
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000475  Protein ID: PT02185
 
Compound ID Compound Name Compound Formula
CP0502049
2-[2-[4-(1,3-benzodioxol-5-yl)-2-(2-chlorophenyl)phenoxy]ethyl-methylamino]acetic acid
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C24H22ClNO5
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0445000
({2-[2'-chloro-5-(2,3-dihydro-benzofuran-5-yl)-biphenyl-2-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C25H24ClNO4
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0444999
({2-[2'-chloro-5-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-biphenyl-2-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C25H24ClNO5
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0515124
({2-[4-(2,3-dihydro-benzofuran-5-yl)-2-thiophen-2-yl-phenoxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C23H23NO4S
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0507864
({2-[4'-methoxy-3'-methyl-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C24H25NO5S
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0464854
({2-[4-benzo[1,3]dioxol-5-yl-2-(thiophene-2-carbonyl)-phenoxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C23H21NO6S
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0505078
({2-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-thiophen-2-yl-phenoxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C23H23NO5S
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0511691
({2-[3'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C22H20ClNO4S
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0444997
({2-[4'-methoxy-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C23H23NO5S
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0434456
2-[2-[2-(2-chlorophenyl)-4-(4-methoxy-3-methylphenyl)phenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C25H26ClNO4
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0560170
2-[2-[4-(1,3-benzodioxol-5-yl)-2-thiophen-2-ylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C22H21NO5S
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0444996
2-[methyl-[2-[4-phenyl-2-(thiophen-2-ylmethyl)phenoxy]ethyl]amino]acetic acid
   Show/Hide
C22H23NO3S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0444998
(methyl-{2-[3'-methyl-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-amino)-acetic acid
   Show/Hide
C23H23NO4S
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0507863
(methyl-{2-[3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-amino)-acetic acid
   Show/Hide
C22H21NO4S
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0505079
2-[2-[2-(2-chlorophenyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C23H22ClNO3
 1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
CP0464853
2-[methyl-[2-[2-(2-methylphenyl)-4-phenylphenoxy]ethyl]amino]acetic acid
   Show/Hide
C24H25NO3
 1
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
CP0503919
(methyl-{2-[4'-methyl-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-amino)-acetic acid
   Show/Hide
C23H23NO4S
 1
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
CP0490609
2-[2-(2-benzoyl-4-phenylphenoxy)ethyl-methylamino]acetic acid
   Show/Hide
C24H23NO4
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0464856
({2-[4'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C22H20ClNO4S
 1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CP0454345
2-[2-[2-(cyclohexanecarbonyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C24H29NO4
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0505081
2-[methyl-[2-(4-phenyl-2-thiophen-2-ylphenoxy)ethyl]amino]acetic acid
   Show/Hide
C21H21NO3S
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0511692
({2-[3',4'-dimethyl-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C24H25NO4S
 1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
CP0493323
2-[2-(2-benzyl-4-phenylphenoxy)ethyl-methylamino]acetic acid
   Show/Hide
C24H25NO3
 1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
CP0464855
({2-[3'-methoxy-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C23H23NO5S
 1
1
IC50 = 104 nM
   TI
   LI
   LO
   TS
CP0454344
2-[2-[2-(2-fluorophenyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C23H22FNO3
 1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CP0464909
2-[methyl-[2-(4-phenyl-2-thiophen-3-ylphenoxy)ethyl]amino]acetic acid
   Show/Hide
C21H21NO3S
 1
1
IC50 = 139 nM
   TI
   LI
   LO
   TS
CP0464858
2-[2-[4-(4-methoxy-3-methylphenyl)-2-thiophen-2-ylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C23H25NO4S
 1
1
IC50 = 161 nM
   TI
   LI
   LO
   TS
CP0464862
({2-[2'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C22H20ClNO4S
 1
1
IC50 = 175 nM
   TI
   LI
   LO
   TS
CP0505080
2-[2-(2,4-diphenylphenoxy)ethyl-methylamino]acetic acid
   Show/Hide
C23H23NO3
 1
1
IC50 = 229 nM
   TI
   LI
   LO
   TS
CP0434458
2-[2-(2-cyclohexyl-4-phenylphenoxy)ethyl-methylamino]acetic acid
   Show/Hide
C23H29NO3
 1
1
IC50 = 251 nM
   TI
   LI
   LO
   TS
CP0445001
2-[2-[2-(cyclohexylmethyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C24H31NO3
 1
1
IC50 = 289 nM
   TI
   LI
   LO
   TS
CP0434457
2-[2-[2-(2-methoxyphenyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C24H25NO4
 1
1
IC50 = 351 nM
   TI
   LI
   LO
   TS
CP0444993
2-[methyl-[2-(2-naphthalen-1-yl-4-phenylphenoxy)ethyl]amino]acetic acid
   Show/Hide
C27H25NO3
 1
1
IC50 = 496 nM
   TI
   LI
   LO
   TS
CP0503920
(methyl-{2-[2'-methyl-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-amino)-acetic acid
   Show/Hide
C23H23NO4S
 1
1
IC50 = 632 nM
   TI
   LI
   LO
   TS
CP0444995
2-[2-[2-(3-chlorophenyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C23H22ClNO3
 1
1
IC50 = 674 nM
   TI
   LI
   LO
   TS
CP0478115
(methyl-{2-[2-(thiophene-2-carbonyl)-4-trifluoromethyl-phenoxy]-ethyl}-amino)-acetic acid
   Show/Hide
C17H16F3NO4S
 1
1
IC50 = 702 nM
   TI
   LI
   LO
   TS
CP0502048
({2-[3',4'-dimethoxy-3-(thiophene-2-carbonyl)-biphenyl-4-yloxy]-ethyl}-methyl-amino)-acetic acid
   Show/Hide
C24H25NO6S
 1
1
IC50 = 834 nM
   TI
   LI
   LO
   TS
CP0444994
2-[methyl-[2-[4-phenyl-2-(1,3-thiazol-2-yl)phenoxy]ethyl]amino]acetic acid
   Show/Hide
C20H20N2O3S
 1
1
IC50 = 957 nM
   TI
   LI
   LO
   TS
CP0505077
2-[2-[2-(4-chlorophenyl)-4-phenylphenoxy]ethyl-methylamino]acetic acid
   Show/Hide
C23H22ClNO3
 1
1
IC50 = 965 nM
   TI
   LI
   LO
   TS