Brief Information of the Cell Line and Protein
Cell Line ID: CL000460 , Flp-In-T-REx-293
Synonyms
Flp-In-T-REx 293
Flp-In T-REx-293
Flp-In T-REx 293
Flp-In T-Rex HEK293
Flp-In 293 T-Rex
Flp-In-T-REx
293-Flip-in-TRex
HEK293 Flp-In T-REx
HEK293FlpIN
293FlpIn T-Rex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_U427
Protein ID: PT04383 , G-protein coupled receptor 84
Gene Name GPR84
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9NQS5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000460  Protein ID: PT04383
 
Compound ID Compound Name Compound Formula
CP0385086
2-hexylsulfanyl-4-hydroxy-1H-pyrimidin-6-one
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C10H16N2O2S
 2
1
EC50 = 0.79 nM
   TI
   LI
   LO
   TS
2
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0063946
CHEBI:4778
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C17H26O4
 2
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
2
EC50 = 630 nM
   TI
   LI
   LO
   TS
CP0059179
1,1-Bis(3''-Indolyl)Methane
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C17H14N2
 2
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
2
EC50 = 1260 nM
   TI
   LI
   LO
   TS
CP0123421
CHEBI:30813
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C10H20O2
 2
1
EC50 = 20000 nM
   TI
   LI
   LO
   TS
2
EC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0544849
9-[(5-cyclopropyl-1,2,4-oxadiazol-3-yl)methoxy]-2-[[(2R)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
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C23H24N4O6
 3
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
2
IC50 = 28 nM
   TI
   LI
   LO
   TS
3
IC50 = 86 nM
   TI
   LI
   LO
   TS
CP0466113
9-(3-anilinoprop-1-ynyl)-2-(1,4-dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
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C26H25N3O4
 3
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 = 22 nM
   TI
   LI
   LO
   TS
3
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0484571
2-[[(2S)-1,4-dioxan-2-yl]methoxy]-9-(oxan-4-ylmethoxymethyl)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
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C24H30N2O6
 3
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
2
IC50 = 83 nM
   TI
   LI
   LO
   TS
3
IC50 = 168 nM
   TI
   LI
   LO
   TS